Active substance AMINALON
Gamma-aminobutyric acid (Acidum gammaaminobutyricum)
1 tablet contains
Gamma Aminobutyric Acid (Aminalon) 250,000 mg
Sucrose (white sugar) - 27,200 mg, magnesium stearate - 2,800 mg, shell: white opadry 200, series 200F280000 or another film-forming system with the specified composition: (polyvinyl alcohol - 4,900 mg, titanium dioxide - 3,500 mg, macrogol (polyethylene glycol) - 1,680 mg, talc - 3.343 mg, methacrylic acid copolymer type C - 0.560 mg, sodium bicarbonate - 0.017 mg) - 14,000 mg.
Description of the dosage form
Round biconvex film-coated tablets of white or almost white color. In cross section, the core is white or almost white.
A nootropic agent, improves the metabolic processes of brain tissue, promotes the utilization of glucose by the brain and the removal of toxic metabolic products from it. It increases the productivity of thinking, improves memory, has a moderate psychostimulating effect, and has a beneficial effect on the restoration of movements and speech after cerebrovascular accident. It has a mild hypotensive effect, reduces the initially high blood pressure (BP) and the severity of symptoms caused by hypertension (dizziness, insomnia), slightly slows down the heart rate. It has a moderate antihypoxic and anticonvulsant effect. In patients with diabetes mellitus, it reduces the glucose content, with a normal blood glucose level, it has the opposite effect (due to glycogenolysis).
Absorption is fast, fairly complete. The time to reach the maximum concentration in the blood plasma is 60 minutes, then the concentration quickly decreases and after 24 hours is not determined.
Residual effects of traumatic brain injury, stroke; cerebrovascular insufficiency, encephalopathy of various genesis, alcoholic encephalopathy, alcoholic polyneuropathy, infantile cerebral palsy, consequences of traumatic brain birth injury in children over 3 years old, mental retardation, motion sickness symptom (sea and air sickness).
Hypersensitivity to the components of the drug, children under 3 years of age, acute renal failure, sucrase / isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption, celiac disease.
Application during pregnancy and lactation
Contraindicated in the first trimester of pregnancy and lactation. Application in the II and III trimester of pregnancy is possible as directed by the attending physician.
Method of administration and dosage AMINALON
Inside, before meals. The daily dose for adults is 3–3.75 g; for children 4-6 years old - 2-3 g / day, over 7 years old - 3 g / day. The daily dose is divided into 3 doses. Treatment is carried out for a long time (from 2-3 weeks to 2-4 months). In case of residual effects of traumatic brain injury, stroke, cerebrovascular insufficiency and encephalopathy of various origins, depending on the nature and severity of the disease, 0.25-0.5-1.0 g is prescribed 3 times a day for 1-3 months.
In alcoholic encephalopathy and polyneuropathy, the dose and duration of treatment are set individually.
With the consequences of craniocerebral trauma and mental retardation in children, aminalone is prescribed in high doses (2-3 g / day) for 2-3 months.
For the purpose of prevention and treatment of motion sickness syndrome for adults - 0.5 g, for children - 0.25 g immediately before using vehicles, or 3 times a day for 3-4 days.
Side effects AMINALON
Nausea, vomiting, insomnia, blood pressure lability, dyspepsia, hyperthermia, dose-dependent side effects increase, allergic reactions may develop.
Enhances the effect of benzodiazepines, many hypnotics and antiepileptic drugs.
In case of an overdose, dose-dependent side effects increase, because allergic reactions described in the section "Possible side effects when using the medicinal product" are dose-independent.
Treatment: gastric lavage, intake of activated charcoal, symptomatic therapy.
In the first days of treatment, fluctuations in blood pressure (BP) are possible.
Information about the possible effect of the medicinal product on the ability to drive vehicles, mechanisms
During the period of treatment, care must be taken when driving vehicles and refrain from engaging in potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions.