Tergynan (ernidazole, nystatin) vaginal tablets

Instructions for Tergynan (ernidazole, nystatin) vaginal tablets

English Product Name
Tergynan

Release Form Tergynan
Vaginal tablets

Description
Vaginal tablets are light yellow, with possible interspersed darker or lighter shades, flat, oblong in shape, beveled at the edges and printed with the letter "T" on both sides.

Active ingredient Tergynan

• prednisone
• ternidazole
• neomycin sulfate
• nystatin

Pharmacotherapeutic group Tergynan

Antimicrobial combined agent (antibiotic+antimicrobial and antifungal agent+antifungal agent+glucocorticosteroid)

Active substances Tergynan
Neomycin+Nistatin+Prednisone+Ternidazole
Release Form
Tablets

Composition Tergynan
1 tablet contains: Active ingredient: ternidazole 200 mg, neomycin sulfate 100 mg (65,000 IU), nystatin 100,000 IU, prednisone sodium metasulphobenzoate 4.7 mg, corresponding to prednisone content of 3 mg. Auxiliary substances: wheat starch - 264 mg, lactose monohydrate - q.s. to 1.2 g, silicon colloidal - 6 mg, magnesium stearate - 10 mg sodium carboxymethyl starch - 48 mg.

• Nosology (ICD codes)
• A59
• Trichomoniasis
• B37.3
• Candidiasis of vulva and vagina
• N76
• Other inflammatory diseases of vagina and vulva
• N77.1
• Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere
• Z29.2
• Another type of prophylactic chemotherapy (use of antibiotics for prophylactic purposes)

Pharmacological effect Tergynan

the combined preparation for topical application in gynecology has antimicrobial, anti-inflammatory, antiprotozoal, antifungal effects; ensures the integrity of the vaginal mucosa and stability of pH.
Ternidazole, an antifungal agent in the imidazole derivatives group, decreases ergosterol synthesis, alters the structure and properties of the cell membrane, has a trichomonacidal effect, and is active against anaerobic bacteria.
Neomycin, a broad-spectrum aminoglycoside antibiotic, is bactericidal against gram-positive and gram-negative organisms.
Nystatin, an antifungal polyene antibiotic, is highly effective against Candida yeast.
Prednisone, a dehydrated analog of hydrocortisone, has anti-inflammatory, anti-allergic, anti-exudative effects.

Method of application and dose

For vaginal administration, one tablet is inserted deep into the vagina while lying down at bedtime. Before administering the tablet should be kept in water for 20-30 seconds. After administration, lie for 10-15 minutes. The average duration of treatment is 10 days; in the case of confirmed mycosis, the duration of treatment can be increased to 20 days; the average duration of preventive treatment is 6 days.

Testimony Tergynan

• treatment of vaginitis caused by antibiotic-sensitive organisms, including
• Bacterial vaginitis;
• Trichomoniasis of the vagina;
• Vaginitis caused by candida
• mixed vaginitis.
• prophylaxis of urogenital infections/vaginitis such as
• Before surgery in gynecology;
• Before birth or abortion;
• before and after insertion of the intrauterine device;
• before and after cervical diathermocoagulation;
• before hysterography.